Our phase sustains higher stability towards basic, neutral, and acidic compounds. Relative retentions changes are minimized throughout the column life.
Hydrolytic stability of columns. Conditions: Columns, (left) Silica (50 mm × 4.6 mm i.d.), (right) FructoShell (50 mm × 4.6 mm i.d.);
flow rate, 1.0 mL/min; eluent: Acetonitrile/ 25 mM NH4OAc pH 6.8, 75/25 (v/v); UV detection at 220 nm. BTMA = butyltrimethylamine
Armstrong et al. Anal. Methods, 2016, 8, 6038-6045
Our column show competitive hydrophilic character while maintaining a low silanol activity
Plot of electrostatic character vs. hydrophilicity character for the evaluated HILIC phases. Conditions: eluent, ACN/25 mM ammonium acetate, pH 6.8, 80/20 (v/v);
flow rate, 1.0 mL/min; UV detection at 254 nm.